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GLP-1 analogues have been shown to have cardiovascular benefits and are generally safe for use in individuals with a history of heart disease
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Moreover, raising awareness about obesity among physicians and prescribing of the condition as a chronic disease has prompted a more aggressive treatment strategy, including the use of GLP-1 receptor agonists and new oral therapies

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These medications appear to reduce the production of pro-inflammatory cytokinessignalling molecules that drive inflammationsuch as tumour necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)
