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This is not a replacement for prescribed medical treatment

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Jejunal circumference, villi length, and crypt depth were significantly greater with cold-stress in WT and DIRKO mice, but not GLPDRKO mice, compared to TN controls

Exclusion criteria included non-English language articles and studies not focusing on cardiovascular, renal or metabolic influences

Reduced regulatory burden: Compliance with GLP can streamline regulatory processes for product approvals
