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For manufacturers that recognize these key factors and have a plan from launch to successfully address them, a path to commercial success can be in reach

Although NASH is a multifactorial disease, in the future we could identify the predominating pathological mechanism and, by choosing the most appropriate specific medication, tailor the treatment for every patient individually.

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Here the authors show the efficacy of GLP1-based multi-agonists, and superiority of GLP1/E, for managing metabolic complications of PCOS in preclinical models, with improvement also of some reproductive traits.

The study was led by first author Dr Sudipta Sen, associate professor, and senior author and Professor Omonele Nwokolo, both from the Department of Anesthesiology, Critical Care and Pain Medicine at McGovern Medical School at UTHealth Houston."Our findings were quite surprising