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Description

Treatment of human and mouse small intestine organoid models with SCFAs increases the number of GLP-1-producing cells twofold 284 , and SCFA infusion activates colonic EECs to increase GLP-1 release in mice 281

For many adults with obesity or weight-related health problems, the potential benefits of GLP-1 treatment can outweigh the risks when the medication is prescribed and monitored by a licensed provider

For one, they may allow people with knee osteoarthritis to avoid or delay knee replacement surgery

Ideal candidates include adults with: BMI 30 (obesity) BMI 27 with weight-related conditions (type 2 diabetes, hypertension, high cholesterol, sleep apnea, PCOS) Inability to lose weight through diet and exercise alone Contraindications include: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN 2) History of pancreatitis (caution advised) Your online doctor will evaluate all risks and benefits before prescribing