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Special caution is required, among other things, in people with a history of pancreatitis, diabetic retinopathy, gastroparesis, or before procedures involving general anaesthesia or deep sedation

The only approvability issue is related to the enrollment status of the confirmatory trials, according to Regenerons announcement

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The researchers note that further studies are needed to determine the causality between the drug and the increased incidence of NAION

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