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However, BMI remained unchanged, indicating that the intracranial pressure effect was likely a direct action of exenatide rather than weight loss alone

A 2023 observational analysis published in the Annals of the Rheumatic Diseases found that patients with inflammatory arthritis who used GLP-1 receptor agonists had lower rates of cardiovascular events, which is notable because cardiovascular disease is a leading cause of death in RA patients

doi: 10.1016/S0140-6736(24)01763-X

Seino S, Welsh M, Bell GI, Chan SJ, Steiner DF

They have accomplished this using advanced techniques such as modifying peptide sequences, lipidating peptides, fusing with albumin, and fusing with Fc
