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While research is rapidly evolving, vascular neurologist Pierre Fayad, MD, says drugs like Ozempic and Wegovy, part of a medication class called GLP-1 agonists, are showing a range of promising results beyond diabetes treatment and weight loss

For research purposes, mazdutide belongs to the incretin mimetic family of peptides

Working with Your Healthcare Provider If you are unsure whether semaglutide is causing your leg cramps, the best thing to do is talk to your healthcare provider

It has been listed as an infrequent side effect of taking GLP-1s, and clinicians and patients have been reminded to be alert to initial symptoms such as severe, persistent stomach pain, accompanied sometimes by nausea and vomiting

Semaglutide may not be suitable for individuals with a personal or familial history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, pancreatitis, or severe gastrointestinal disease
