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For example, clarithromycin has been noted to occasionally result in hypoglycemia, especially when used with insulin and other diabetes medications

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Pancreatic and Thyroid Risks: While rare, there are concerns about potential risks such as acute pancreatitis, gallbladder disease, and an increased risk of thyroid C-cell tumors (based on animal studies)

In the UK the drugs are only available with permission from a medical doctor, who will issue a prescription only if the patient satisfies the rigorous eligibility criteria