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Caution when using GLP-1 RAs in older patients, especially those 75 years old, has been suggested to prevent the risk of sarcopenia
These drugs also lower postprandial TGs and apoB48 in humans (5, 14, 15) and in mice through mechanisms requiring the GLP-1R (9)
Unlike phentermine, semaglutide is administered as a once-weekly subcutaneous injection and is approved for long-term use
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Existing trials in humans have been small in size, she adds
