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In contrast, high doses of GLP1/E had negligible effects on glucose control, insulin sensitivity, or circulating glucose and insulin levels (Fig

Exenatide, a synthetic variant of exendin-4, incorporates strategic modifications that substitute asparagine (Asn) at the C-terminal with aspartic acid (Asp) and swap alanine (Ala) at the 8 th position with glycine (Gly)

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Future Directions and Precision Medicine Future research should focus on several key areas

J Clin Invest 91: 301307
