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Dan Frommer's New Consumer Trends 2026 report provides a snapshot for US-based GLP-1 users, which is quite insightful

Observing rs-fMRI, the functional brain connectivity in GLP-1R KO mice was significantly lower than that in the WT group (p=0.0032 for gFCD, p=0.0002 for whole-brain correlation, p<0.0001 for ALFF)