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And nausea tends to sit in the background of all of this

During colder Canadian winters, medication may take longer to reach room temperature after removal from refrigeration

A smaller percentage may experience persistent but manageable diarrhea throughout therapy

The good news: the $50 GLP-1 Bridge runs through a single central processornot your individual plan so your plan doesn't have to opt in or add Foundayo to its formulary for you to get Bridge coverage
Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users
