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Importantly, GLP-1 is a potent inhibitor of pancreatic glucagon secretion [46]

At the 1mg dose, roughly 14% of participants reported nausea

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These drugs are resulting in less acetaldehyde. The findings suggest that not only might GLP-1 receptor agonists help the liver by acting on the brain to reduce alcohol consumption, but also through slowing metabolism of alcohol in the liver, and in turn reducing the levels of toxic metabolites

Coffee can be a gastric irritant
