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SURMOUNT-1 (NEJM, 2022) the Tirzepatide Phase 3 trial enrolled 2,539 participants

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The FDA warns against it explicitly

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The largest study to date that analyzed patterns of GLP1 RA use in breast cancer survival was a retrospective study that analyzed roughly 1022 patients with nonmetastatic (DCIS or invasive stage IIII) at MD Anderson Cancer Center who received at least 3 months of semaglutide and tirzepatide