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Food and Drug Administration (FDA) started approving them for chronic weight management in 2021, according to new data published in the Journal of Medical Toxicology .[1] GLP-1 medications such as semaglutide, sold by Novo Nordisk under the brand name Wegovy, were originally developed to treat diabetes

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For cagrilintide , the most significant trial programme involves its combination with semaglutide (CagriSema), investigated in the REDEFINE trial series