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Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A
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17 Interestingly, GLP-1 levels are elevated in critically ill patients in different chronic inflammatory diseases including CD, UC, metabolic syndrome, coronary artery disease, and heart failure, and have been found to be increased in animal models of inflammatory conditions in response to bacterial stimuli, suggesting a correlation between inflammation and GLP-1 secretion
This is the most common reason people find treatment difficult to tolerate

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