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However, heterogeneity in weight loss response, cost, side effects, and need for injections may limit their use in many pediatric patients

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In the subgroup analyses, human GLP-1 RAs, but not nonhuman GLP-1 RAs, reduced the risk of MACE in patients with HF (p interaction = 0.11)

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Companies operating in this space may benefit from reviewing their promotional materials to ensure alignment with FDA expectations

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