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Brain activity profiling of GLP-1MK-801 Encouraged by the transcriptomic data indicating that the weight loss is evoked through a mechanism of action involving the combined pharmacological actions of NMDA receptor antagonism and GLP-1 receptor agonism in the hypothalamus, we performed a comprehensive comparison between GLP-1MK-801 and the long-acting GLP-1 receptor agonist, semaglutide

doi: 10.3390/ijms20215407

Kridin K

In a diabetic mouse model, administration of GLP-1RA-ELP-FGF21 reduced glycaemia without incidences of hypoglycaemia and greater body weight reductions compared with the monotherapy or an equimolar mixture of GLP1-ELP and ELP-FGF21 (94)

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