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FIGURE 2 5.1 Anti-neuroinflammatory effects The principal mechanism by which semaglutide exerts its neuroprotective effects is through the suppression of neuroinflammation

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Metric Definitions Numerator Patients who received a prescription, medication dispense, or reported starting a GLP-1 medication in the quarter

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Chambers AP, Sorrell JE, Haller A, Roelofs K, Hutch CR, Kim K-S, Gutierrez-Aguilar R, Li B, Drucker DJ, DAlessio DA, Seeley RJ, Sandoval DA

Abstract Glucagonlikepeptide1 (GLP1) derived from gut enteroendocrine cells and a discrete population of neurons in the caudal medulla acts through humoral and neural pathways to regulate satiety, gastric motility and pancreatic endocrine function