glp 1 receptor agonists in idiopathic intracranial hypertension GLP-1 Hypertension: A Systematic Review | Headache Journal (Headache: The Journal of Head & Face Pain) posted on the topic Effect of glucagon like peptide-1
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The mean half-life was about 6 days
Dahl, D
BMJ Open 2013
This strategy has been applied to dulaglutide, where two GLP-1 molecules are fused to the Fc fragment of IgG4, increasing the half-life while reducing the renal elimination due to the increased molecular weight
