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Analysis software Modeling and simulation were conducted using NONMEM 7.4 (ICON Development Solutions, USA), and model parameter estimation was performed using the First-Order Conditional Estimation method (FOCE-I)

In addition, their impact on gastric motility has raised perioperative concerns, particularly related to delayed gastric emptying, which increases the risk of vomiting and aspiration during induction of general anesthesia

doi: 10.1016/S1262-3636(17)30070-8 196 DongZZhuangQYeXNingMWuSLuLet al

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These medications represent promising options for individuals seeking effective and sustainable solutions for weight management and overall metabolic health