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10.1172/JCI1349 [DOI] [PMC free article] [PubMed] [Google Scholar] 28.Park CK, Go EJ, Jo H, Hwang SM, Rahman MM, Park J, Lee JY, Jo YY, Jung Y, Berta T, Kim YH (2024) GLP-1 and its derived peptides mediate Pain Relief through Direct TRPV1 inhibition without affecting Thermoregulation
doi: 10.1016/j.pharmthera.2022.108270
GCGR activation, represented in green, is unique in that glucagon receptors are robustly expressed on hepatocytes, enabling direct liver-directed metabolic effects - a mechanistic feature absent from both GLP-1R and GIPR signaling
doi: 10.1016/j.ceca.2012.03.003
N Engl J Med 370: 794-797, 2014
