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Oncology Times , 44

21 Several studies suggest that the neuroprotective actions of GLP-1 medicines may also be mediated by improvements in brain insulin resistance and glucose metabolism, in part through restoration of impairments in insulin receptor substrate 1 phosphorylation, 22 effectively re-establishing functional central insulin signaling, although the data linking GLP-1 action to central insulin signaling are limited

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2013;304(12):G11171127