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Based on these results, Hanmi plans to initiate Phase 2 clinical trials in the second half of 2025, evaluating the long-term effects of HM15275 in reducing body weight and preserving lean mass in patients with severe obesity

Evidence has shown, however, that most people who stop taking the drugs gain at least some of the weight back

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Unlike some psychiatric drug candidates where the mechanism of action is poorly understood, the GLP-1 pathway in reward circuitry has been extensively mapped
