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As the disease progresses, clinical manifestations may emerge, including, but not limited to, refractory hypertension, peripheral or generalized edema, glaucoma, proteinuria characterized by foamy urine, and a range of systemic complications, such as cardiac, neurological and respiratory disorders [23,24,25,26]
Cyanocobalamin is a vitamin in the B-complex family and is usually known as cobalamin

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