glp 1 and addiction treatment GLP-1 Addiction: Clinical Trials Testing Ozempic for Recovery Mechanisms of GLP-1 in Modulating

As I explore the potential of STDEI GLP-1, I'm intrigued by how this medication could transform diabetes management

Similarly to type 1 diabetes, it has no cure, and treatment is aimed at relieving the most uncomfortable of symptoms

Learn about GLP-1 medications, reported side effects like gastroparesis and vision loss, and when legal questions may arise

Others * Long-term metformin use * Proton pump inhibitors (reduce acid absorption) Pathophysiology * Impaired DNA synthesis megaloblastic anemia * Accumulation of methylmalonic acid nerve damage Clinical features Hematological * Fatigue, pallor * Shortness of breath * Megaloblastic anemia Neurological (key distinguishing feature) * Peripheral neuropathy (tingling, numbness) * Loss of vibration and position sense * Ataxia (unsteady gait) * Cognitive changes Severe untreated cases irreversible nerve damage Others * Glossitis (smooth, beefy red tongue) * Mild jaundice Investigations * Serum vitamin B12 * CBC macrocytic anemia ( MCV) * Blood film hypersegmented neutrophils * methylmalonic acid (specific for B12 deficiency) * homocysteine Differentiate from folate deficiency * Both megaloblastic anemia * Only B12 neurological symptoms Management Replacement therapy * Hydroxocobalamin (preferred IM) * Frequent doses initially, then maintenance * Oral B12 if mild and absorption intact Important rule Never give folate alone if B12 deficiency is possible may worsen neurological damage Prevention * Adequate diet (meat, eggs, dairy) * Supplementation in vegans * Monitor high-risk patients (elderly, post-surgery)

We are proud to share that Professor Jens Juul Holst from the Department of Biomedical Sciences has been awarded the Lipid Science Prize 2026 by the Camurus Lipid Research Foundation in Malm. Jens receives the prize in recognition of his groundbreaking discovery of the GLP1 hormone back in 1986 - a finding that laid the foundation for diabetes and weightloss medications used by millions worldwide