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Research design and methods Using the data from the United States Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) databases, the differences in adverse events across specific subgroups concerning reporter type, sex, age, dose, indication, report year, onset time, and outcome were investigated using the ROR algorithm and Chi-Square Test/Fishers exact test

Evidence-based dose conversion from semaglutide to tirzepatide, why direct milligram equivalency fails, and the step-up protocol providers actually use.