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Mayo Clinics ENDO 2025 study of 120 postmenopausal women found tirzepatide plus HRT produced 17% weight loss vs 14% alone over 18 months, with 45% of HRT users hitting 20%+ loss vs 18% of non-users (see our tirzepatide vs semaglutide analysis)
The American Diabetes Association does not recommend probiotics or other dietary supplements for glycemic control due to insufficient evidence
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Yet many pediatricians do not prescribe drugs such as metformin and Qsymia directly to pediatric patients but instead refer them to weight management programs, pediatric obesity experts, or endocrinologists who can issue prescriptions
