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Types of GLP-1-related medications The term "GLP-1 receptor agonists" typically refers to a class of injectable (or sometimes oral) drugs originally developed for Type 2 diabetes and now widely used for obesity/weight management

Energy-dense diet triggers changes in gut microbiota, reorganization of gut-brain vagal communication and increases body fat accumulation

Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions

Appl Physiol Nutr Metab 33:929935

People who develop fat-adapted metabolism, learn keto food preparation, and build sustainable ketogenic eating patterns during their semaglutide course have a functional maintenance strategy available when they eventually taper off