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Given the success of incretin-based drugs in treating both diabetes and obesity, and their potential for treating NAFLD, further dissection of the regulation of hepatic metabolic pathways by DPP4 is warranted (2733)

Clinical observations from patients treated with GLP1 receptor agonists for Type 2 diabetes suggest that GLP1 receptor agonists may reduce body weight more in subjects with higher baseline body mass index (Niswender et al., 2013), so, in future clinical trials, it may be useful to evaluate the effects of GLP1 receptor agonists on alcohol intake in more specific subgroups of AUD patients, for example, in AUD patients with comorbid obesity

The inactivated conjugate displayed comparable plasma stability and human serum albumin (HSA) binding properties to GLP-1MK-801 (Fig

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