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Combining EXE with PIO also suppressed the significant change in body weight induced by PIO compared to weight gain found after its administration

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Anti-Obesity Effect of Pine Needle Extract on High-Fat Diet-Induced Obese Mice

In recent years, GLP-1 medications like Ozempic have progressed from a specialised diabetes treatment into a more widespread weight loss tool used by a wide range of people globally

Central GLP-1R activation in hypothalamic and mesolimbic pathways may lead to fatigue, lethargy, or brain fog 63 , though such effects might be often transient and dose-dependent