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These individuals appear to have a puzzling condition called GLP-1 resistance, where their bodies produce higher levels of the hormone targeted by these drugsbut dont respond to it properly.

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To conclude, the food intake reducing effects of exenatide may temporally evolve from strong anorectic to weak anhedonic modulations, where hedonic experience and anticipation during the early anorectic phase is conserved but uncoupled from food intake behaviour.

Together, these presentations reflect continued progress across the elecoglipron clinical program and its potential as a once-daily oral GLP-1 receptor agonist for people living with obesity, overweight, or type 2 diabetes