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Our study offers novel insights as the first project to link biological consequences of weight loss, namely lower leptin and reduced GLP-1, to eating larger amounts of food, which is a core feature of binge eating, said co-author Lindsay Bodell, a professor in the Department of Psychology at Western University in Ontario, Canada

The medication is administered as a once-weekly subcutaneous injection, with dosing gradually increased over several weeks to minimize gastrointestinal side effects

Increased clinical monitoring of thyroid parameters should also be considered when treating patients with both semaglutide and oral levothyroxine

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Regulators have also identified counterfeit pens made to closely resemble approved products