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This evidence supports the model that GLP-1 medications work best as ongoing therapies rather than short-term interventions

Results showed that liraglutide-treated patients achieved significantly greater weight loss compared to placebo over 24 weeks

Our findings broadly support the recommendation against use of these medications in both pregnancy and during lactation, in particular given effective and safe alternatives are available

Obesity 21 , 935943 (2013)

Additionally, the improved insulin sensitivity from GIP receptor activation may help your muscles take up amino acids more efficiently, supporting muscle protein synthesis even during a caloric deficit