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doi:10.1016/0014-5793(95)01070-U

Some head-to-head studies later compared exenatide BID to insulin or to newer GLP-1 RAs

Additional Information and Resources: FDA updates Ozempic label to acknowledge some users reports of blocked intestines

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Also, the combination of GLP-1 agonists with SGLT-2 inhibitors and novel insulin sensitizers are under investigation as a triple combination therapy for patients with diabetes resistant to various current dual therapy regimens, and initial trials are encouraging in reaching glycemic goals in patients who have failed to respond to traditional dual therapy interventions