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This review aims to provide a comprehensive overview of tirzepatide's emerging therapeutic roles beyond glycemic control and weight loss, including its potential benefits in cardiovascular, hepatic, renal, and neurological health

Relevant factors include tolerability, pre-existing conditions, concurrent medication, and the course of treatment so far

Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

While their glucose-lowering effects have been well documented for years, recent clinical breakthroughs have shown that these medications can deliver transformative weight loss, often rivalling or even surpassing results from bariatric surgery for certain patients