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Combination users were matched, in a 1:1 ratio, to patients prescribed the same background drug, duration of background drug, and time conditional propensity score

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GLP-Pre is formulated with essential prebiotics that act as food for GLP-1 producing cells in the gut

Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

Clinically, that translates to: More stable post-meal glucose Better appetite regulation Reduced energy crashes Improved satiety Mechanistically: GLP-1 slows gastric emptying, signals fullness centrally, supports insulin secretion, and suppresses glucagon