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Nausea is the most commonly reported symptom with both treatments, particularly during the dose-escalation phase

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Why Tirzepatide Is Not Recommended During Pregnancy Tirzepatide has not been formally studied in pregnant women, which means its effects on fetal development, placental function, and pregnancy outcomes are not well documented in clinical trials

Common symptoms include nausea, heartburn, constipation, diarrhea, and occasional fatigue

received speaking honoraria from Abbott Diabetes Care, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Dexcom, GSK, Eli Lilly and Company, HLS Therapeutics, Insulet, Janssen, Novo Nordisk, Pfizer, and Sanofi