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Therefore, a comprehensive study examining the effects of GLP-1 exposure at various time points with different doses, both before and during pregnancy (despite limited human data), will be conducted in the future

DOI: 10.2337/dc17-er06c 17

Cost variability: Both can be costly

Set point resistance : Your body defends against further weight loss through hormonal shifts, including changes in leptin, ghrelin, and insulin sensitivity, that increase hunger and slow metabolism

Valid reasons for switching include hitting a genuine plateau after months on stable dose, persistent side effects that do not resolve with time and management strategies, or availability and cost considerations that make the current peptide unsustainable