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Description
Tirzepatide also activates GIP receptors, which may produce a slightly different gastrointestinal symptom profile in some patients

These medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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Oversight remains minimal, even as prescriptions surge

Note: These are guideline-based indications at a population level
