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Preclinical studies indicate that DPP4-is may alleviate pain-related behaviors in models of nerve injury and diabetes-induced neuropathy, perhaps through mechanisms such as the suppression of pro-inflammatory cytokines, inhibition of glial cell activation, and enhancement of neuronal survival [10]
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Anti-proliferative effect of pro-inflammatory cytokines in cultured cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1

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