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Systematic rotation of injection sites is a fundamental practice for patients using injectable medications, essential for preventing complications and maintaining optimal therapeutic outcomes

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reported in the early 90 s that GLP-1 interacted with exendin receptors on dispersed acini from guinea pig pancreas 22,23 , and these concerns were increased with the results from the LEADER trial showing a numerically greater, although statistically not significant, number of cases of pancreatic cancer in the liraglutide arm compared to the placebo 20

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