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The most common side effects of tirzepatide injections include nausea, decreased appetite, and stomach problems, especially during the early stages of treatment

By contrast, prescribing semaglutide for eligible patients is a standard, evidence-based practice

Blonde L, Rosenstock J, Del Prato S, et al

Red flag symptoms requiring urgent GP consultation include abnormal vaginal bleeding, severe vulval pain or fissuring, pelvic pain, fever, spreading cellulitis, severe balanitis, difficulty retracting the foreskin with pain and swelling (possible paraphimosis), or symptoms that do not resolve with standard antifungal treatment

Meanwhile, newer 2026 research indicates that Tirzepatide provides significant benefits for individuals struggling with sleep apnea or fatty liver disease