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If you do need to take omeprazole for an extended period, its worth knowing that long-term use may: increase the risk of a gut infection called Clostridioides difficile , which can cause severe diarrhoea mask the symptoms of stomach cancer, which is why its important to have any persistent or unusual symptoms investigated before starting treatment increase the risk of bone fractures, particularly in older people increase the risk of pneumonia lower magnesium levels in the body, which can cause tiredness, muscle weakness, dizziness, and in some cases, more serious effects like convulsions or an irregular heartbeat If you have any concerns about taking omeprazole long-term, speak to your GP or prescriber

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