glp-1 drug updates Medicare is about to cover drugs for weight loss. Here's what to know While many patients are seeing

Emerging preclinical evidence suggests GLP-1 may influence neuronal survival, synaptic plasticity, and neuroinflammationprocesses that are disrupted in neurodegenerative conditions

doi: 10.1038/s41598-024-57724-5

For spinal cord staining, we used mice not injected with AAV-9

In standard functional assays, orforglipron shows greater than 100-fold selectivity for the GLP-1 receptor over the glucagon receptor, the GIP receptor, and the secretin receptor

A significant concern is that the most common adverse effects of GLP-1 agonistsnausea, vomiting, diarrhea, and abdominal painoverlap substantially with Crohn's disease symptoms