glp-1 small molecule agonist Oral Small-Molecule Receptor Agonists: Mechanistic Insights and Emerging Therapeutic Strategies Small-molecule agonists activate the Ga
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Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin

These dual RAs are being evaluated mainly in T2D, T1D, overweight/obesity, and few other possible indications (Figure 2)
Excitement has grown in this drug class, with several GLP-1R agonists demonstrating benefit in cardiovascular outcomes studies ( 10 )

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