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Biologia 75:20632071 Thiry A, Dogne J-M, Supuran CT, Masereel B (2008) Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action

A key question is how their spatial restriction is regulated

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Preclinical studies suggest that GLP1 and serotonin comodulate hypothalamic appetite regulation via alphamelanocytestimulating hormone (MSH) signalling, supporting further investigation into potential applications in anorexia nervosa and bulimia nervosa