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[DOI] [PubMed] [Google Scholar] 28.Cho Y.M., Fujita Y., Kieffer T.J

Table 3 shows the estimated decrease in A1c levels for different drugs in patients that are drug nave with an A1c of 8% and a weight of 90kg after 26 weeks of treatment
They enhance glucose-dependent insulin secretion, suppress glucagon release, delay gastric emptying, and reduce appetite, thereby contributing to glucose homeostasis and body weight regulation (29, 30)

(1984) Pre-proglucagon messenger ribonucleic acid: nucleotide and encoded amino acid sequences of the rat pancreatic complementary deoxyribonucleic acid

In the long term, it can lead to sarcopeniaage-related muscle losswhich increases the risk of falls, fractures, and other mobility issues