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doi: 10.1523/JNEUROSCI.2105-10.2010

Drinking even a little can add a lot of extra energy, which makes losing weight tougher

The binding assays suggested that the N-terminal positions 7, 10, 12, 13 and 15 were important for GLP-1 affinity at rGLP-1R since the substitutions resulted in a 41- to 219-fold increase in IC 50

administered native GLP-1 on eating [694], because GLP-1 infusions into the hepatic portal vein did not lose their potency to reduce food intake after subdiaphragmatic vagal deafferentation in rats [692,694]

Sioux Falls therapist Faith Carlson said the GLP-1s are good, but offered some caution
