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If fatigue persists beyond the initial adjustment period or significantly impacts daily functioning, further evaluation is warranted to identify underlying causes
Psychiatry 28 , 543552 (2023)
[DOI] [PubMed] [Google Scholar] 15.Jha M.K., Jo M., Kim J.H., Suk K
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Binding of -MSH to MC4R triggers a Gs protein-coupled signaling cascade, which increases intracellular cyclic AMP (cAMP) levels and ultimately activates downstream pathways that promote satiety and increase energy expenditure [9]
